Conserved structural, pharmacological and functional properties among the three human and five zebrafish α(2)-adrenoceptors

1. Zebrafish has five distinct α(2)-adrenoceptors. Two of these, α(2Da) and α(2Db), represent a duplicated, fourth α(2)-adrenoceptor subtype, while the others are orthologue of the human α(2A)-, α(2B)- and α(2C)-adrenoceptors. Here, we have compared the pharmacological properties of these receptors...

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Main Authors: Ruuskanen, Jori O, Laurila, Jonne, Xhaard, Henri, Rantanen, Ville-Veikko, Vuoriluoto, Karoliina, Wurster, Siegfried, Marjamäki, Anne, Vainio, Minna, Johnson, Mark S, Scheinin, Mika
Format: Artigo
Language:Inglês
Published: 2005
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575993/
https://ncbi.nlm.nih.gov/pubmed/15655522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706057
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