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Protein kinase C activation inhibits eosinophil degranulation through stimulation of intracellular cAMP production

1. The mechanism of inhibition of eosinophil degranulation by protein kinase C (PKC) was investigated in complement C5a (C5a)-stimulated degranulation of highly purified human eosinophils using the specific PKC activator – phorbol 12-myristate 13-acetate (PMA). 2. C5a-induced release of eosinophil p...

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Detalhes bibliográficos
Main Authors: Ezeamuzie, Charles I, Taslim, Najla
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575935/
https://ncbi.nlm.nih.gov/pubmed/15504748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706028
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