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Coupling of the human A(1) adenosine receptor to different heterotrimeric G proteins: evidence for agonist-specific G protein activation

1. The present study investigates the effect of varying ligand structure on the ability of agonists to activate guanine nucleotide-binding proteins of the Gi, Gs and Gq families via the A(1) adenosine receptor. 2. In CHO cells expressing this receptor, inhibition or potentiation of forskolin-stimula...

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Detalhes bibliográficos
Main Authors: Cordeaux, Yolande, IJzerman, Adriaan P, Hill, Stephen J
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575922/
https://ncbi.nlm.nih.gov/pubmed/15302686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705925
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