Tyrosine phosphorylation of p62(dok) by p210(bcr-abl) inhibits RasGAP activity
The t(9;22) chromosomal translocation is found in almost all patients with chronic myelogenous leukemia. The resultant Bcr-Abl fusion gene expresses a chimeric fusion protein p210(bcr-abl) with increased tyrosine kinase activity. Hematopoietic progenitors isolated from chronic myelogenous leukemia p...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15759/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688886/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040547997 |
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