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Inhibition of TRPM2 function by PARP inhibitors protects cells from oxidative stress-induced death

TRPM2 is a member of the transient receptor potential (TRP) protein superfamily of calcium-permeable, voltage-independent ion channels expressed in nonexcitable cells. Activation of TRPM2 by oxidative stress results in calcium influx and susceptibility to cell death, whereas inhibition of TRPM2 func...

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Detalhes bibliográficos
Autor principal: Miller, Barbara A
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575424/
https://ncbi.nlm.nih.gov/pubmed/15514246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705923
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