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The Poly(ADP-ribose) Polymerase PARP-1 Is Required for Oxidative Stress-induced TRPM2 Activation in Lymphocytes

TRPM2 cation channels are widely expressed in the immune system and are thought to play a role in immune cell responses to oxidative stress. Patch clamp analyses suggest that TRPM2 channel activation can occur through a direct action of oxidants on TRPM2 channels or indirectly through the actions of...

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Detalles Bibliográficos
Main Authors: Buelow, Ben, Song, Yumei, Scharenberg, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259813/
https://ncbi.nlm.nih.gov/pubmed/18599483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802673200
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