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Allergic sensitization enhances the contribution of Rho-kinase to airway smooth muscle contraction

1. Repeated allergen challenge has been shown to increase the role of Rho-kinase in airway smooth muscle (ASM) contraction. We considered the possibility that active allergic sensitization by itself, that is, without subsequent allergen exposure, could be sufficient to enhance Rho-kinase-mediated AS...

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Autores principales: Schaafsma, Dedmer, Gosens, Reinoud, Bos, I Sophie T, Meurs, Herman, Zaagsma, Johan, Nelemans, S Adriaan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575413/
https://ncbi.nlm.nih.gov/pubmed/15381630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705903
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