Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors

1. Co-administration of the calcineurin inhibitor cyclosporine and the mTOR inhibitors sirolimus or everolimus increases the efficacy of immunosuppression after organ transplantation. However, clinical studies showed enhancement of cyclosporine toxicity. To characterize the biochemical mechanisms in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Christians, Uwe, Gottschalk, Sven, Miljus, Jelena, Hainz, Carsten, Benet, Leslie Z, Leibfritz, Dieter, Serkova, Natalie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2004
Pynciau:
Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575349/
https://ncbi.nlm.nih.gov/pubmed/15339861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705939
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