Low-Salt Diet and Cyclosporine Nephrotoxicity: Changes in Kidney Cell Metabolism

Cyclosporine (CsA) is a highly effective immunosuppressant used in patients after transplantation; however its use is limited by nephrotoxicity. Salt depletion is known to enhance CsA-induced nephrotoxicity in the rat, but the underlying molecular mechanisms are not completely understood. The goal o...

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Main Authors: Klawitter, Jelena, Klawitter, Jost, Schmitz, Volker, Brunner, Nina, Crunk, Amanda, Corby, Kyler, Bendrick-Peart, Jamie, Leibfritz, Dieter, Edelstein, Charles L., Thurman, Joshua M., Christians, Uwe
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831655/
https://ncbi.nlm.nih.gov/pubmed/23057591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr300260e
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