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Molecular pharmacological profile of the nonredox-type 5-lipoxygenase inhibitor CJ-13,610

1. 5-Lipoxygenase (5-LO) is a crucial enzyme in the synthesis of the bioactive leukotrienes (LTs) from arachidonic acid (AA), and inhibitors of 5-LO are thought to prevent the untowarded pathophysiological effects of LTs. 2. In this study, we present the molecular pharmacological profile of the nove...

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Bibliografiske detaljer
Main Authors: Fischer, Lutz, Steinhilber, Dieter, Werz, Oliver
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575070/
https://ncbi.nlm.nih.gov/pubmed/15197110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705860
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