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A quantitative and comparative study of the effects of a synthetic ciguatoxin CTX3C on the kinetic properties of voltage-dependent sodium channels

1. Ciguatoxins (CTXs) are known to bind to receptor site 5 of the voltage-dependent Na channel, but the toxin's physiological effects are poorly understood. In this study, we investigated the effects of a ciguatoxin congener (CTX3C) on three different Na-channel isoforms, rNa(v)1.2, rNa(v)1.4,...

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Hlavní autoři: Yamaoka, Kaoru, Inoue, Masayuki, Miyahara, Hidemichi, Miyazaki, Keisuke, Hirama, Masahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575065/
https://ncbi.nlm.nih.gov/pubmed/15197105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705852
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