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Acute and long-term effects of nateglinide on insulin secretory pathways

1. Acute and chronic effects of the insulinotropic drug nateglinide upon insulin release were examined in the BRIN-BD11 cell line. 2. Nateglinide (10–400 μM) stimulated a concentration-dependent increase (P<0.05–P<0.001) in insulin release at a non-stimulatory (1.1 mM) glucose concentration. T...

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Autors principals: Ball, Andrew J, Flatt, Peter R, McClenaghan, Neville H
Format: Artigo
Idioma:Inglês
Publicat: 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574948/
https://ncbi.nlm.nih.gov/pubmed/15155541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705766
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