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Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide
1. Acute and chronic mechanisms of action of novel insulinotropic antidiabetic drug, BTS 67 582 (1,1-dimethyl-2-(2-morpholinophenyl)guanidine fumarate), were examined in the stable cultured BRIN-BD11 cell line. 2. BTS 67 582 (100–400 μM) stimulated a concentration-dependent increase (P<0.01) in i...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2000
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572067/ https://ncbi.nlm.nih.gov/pubmed/10807689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703306 |
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