Llwytho...

Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide

1. Acute and chronic mechanisms of action of novel insulinotropic antidiabetic drug, BTS 67 582 (1,1-dimethyl-2-(2-morpholinophenyl)guanidine fumarate), were examined in the stable cultured BRIN-BD11 cell line. 2. BTS 67 582 (100–400 μM) stimulated a concentration-dependent increase (P<0.01) in i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: McClenaghan, Neville H, Ball, Andrew J, Flatt, Peter R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572067/
https://ncbi.nlm.nih.gov/pubmed/10807689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703306
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