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Development and Functional Characterization of Insulin-releasing Human Pancreatic Beta Cell Lines Produced by Electrofusion

Three novel human insulin-releasing cell lines designated 1.1B4, 1.4E7, and 1.1E7 were generated by electrofusion of freshly isolated of human pancreatic beta cells and the immortal human PANC-1 epithelial cell line. Functional studies demonstrated glucose sensitivity and responsiveness to known mod...

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Detalhes bibliográficos
Main Authors: McCluskey, Jane T., Hamid, Muhajir, Guo-Parke, Hong, McClenaghan, Neville H., Gomis, Ramon, Flatt, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121343/
https://ncbi.nlm.nih.gov/pubmed/21515691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.226795
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