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Agonist-dependence of recovery from desensitization of P2X(3) receptors provides a novel and sensitive approach for their rapid up or downregulation

1. Fast-desensitizing P2X(3) receptors of nociceptive dorsol root ganglion (DRG) neurons are thought to mediate pain sensation. Since P2X(3) receptor efficiency is powerfully modulated by desensitization, its underlying properties were studied with patch-clamp recording. 2. On rat cultured DRG neuro...

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Hlavní autoři: Sokolova, Elena, Skorinkin, Andrei, Fabbretti, Elsa, Masten, Lara, Nistri, Andrea, Giniatullin, Rashid
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574273/
https://ncbi.nlm.nih.gov/pubmed/14980981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705701
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