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Aromatic residues at position 55 of rat α7 nicotinic acetylcholine receptors are critical for maintaining rapid desensitization
The rat α7 nicotinic acetylcholine receptor (nAChR) can undergo rapid onset of desensitization; however, the mechanisms of desensitization are largely unknown. The contribution of a tryptophan (W) residue at position 55 of the rat α7 nAChR subunit, which lies within the β2 strand, was studied by mut...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375650/ https://ncbi.nlm.nih.gov/pubmed/18096596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.149492 |
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