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Desensitization properties of P2X3 receptors shaping pain signaling
ATP-gated P2X3 receptors are mostly expressed by nociceptive sensory neurons and participate in transduction of pain signals. P2X3 receptors show a combination of fast desensitization onset and slow recovery. Moreover, even low nanomolar agonist concentrations unable to evoke a response, can induce...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854565/ https://ncbi.nlm.nih.gov/pubmed/24367291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00245 |
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