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Studies on the mechanisms of action of picrotoxin, quercetin and pregnanolone at the GABAρ(1) receptor

1. The mechanisms of action of antagonists of the γ-aminobutyric acid C (GABA(C)) receptor picrotoxin, quercetin and pregnanolone were studied. 2. Ionic currents (chloride), mediated through human homomeric GABAρ(1) receptors expressed in Xenopus oocytes, were recorded by two-electrode voltage clamp...

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Detalhes bibliográficos
Main Authors: Goutman, Juan D, Calvo, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574239/
https://ncbi.nlm.nih.gov/pubmed/14732759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705657
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