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Analysis of macroscopic ionic currents mediated by GABAρ(1) receptors during lanthanide modulation predicts novel states controlling channel gating

1. Lanthanide-induced modulation of GABA(C) receptors expressed in Xenopus oocytes was studied. 2. We obtained two-electrode voltage-clamp recordings of ionic currents mediated by recombinant homomeric GABAρ(1) receptors and performed numerical simulations of kinetic models of the macroscopic ionic...

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Detalhes bibliográficos
Main Authors: Goutman, Juan D, Escobar, Ariel L, Calvo, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751227/
https://ncbi.nlm.nih.gov/pubmed/16231008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706411
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