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Chronic oral supplementation with sepiapterin prevents endothelial dysfunction and oxidative stress in small mesenteric arteries from diabetic (db/db) mice
1. We previously reported that acute incubation with tetrahydrobiopterin (BH(4)) or sepiapterin, a cofactor for endothelial nitric oxide synthase and a stable precursor of BH(4), respectively, enhanced the acetylcholine (Ach)-induced relaxation of isolated small mesenteric arteries (SMA) from diabet...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574066/ https://ncbi.nlm.nih.gov/pubmed/14534153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705476 |
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