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Cellular basis of endothelial dysfunction in small mesenteric arteries from spontaneously diabetic (db/db −/−) mice: role of decreased tetrahydrobiopterin bioavailability

1. Endothelium-dependent and -independent regulation of vascular tone in small mesenteric arteries (SMA) from control (db/db +/?) and diabetic (db/db −/−) mice was compared. 2. Phenylephrine-induced maximum contraction, but not sensitivity, of SMA in db/db −/− compared to db/db +/? was enhanced. 3....

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Detalhes bibliográficos
Main Authors: Pannirselvam, Malarvannan, Verma, Subodh, Anderson, Todd J, Triggle, Chris R
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573335/
https://ncbi.nlm.nih.gov/pubmed/12010774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704683
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