Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1

1. The 2-(p-chlorophenoxy)propionic acid (CPP) modulates in a stereoselective manner the macroscopic chloride conductance (gCl), the electrical parameter sustained by the CLC-1 channel, of skeletal muscle. In order to determine the structural requirements for modulating native gCl and to identify hi...

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Detalhes bibliográficos
Main Authors: Liantonio, Antonella, De Luca, Annamaria, Pierno, Sabata, Didonna, Maria Paola, Loiodice, Fulvio, Fracchiolla, Giuseppe, Tortorella, Paolo, Laghezza, Antonio, Bonerba, Elisabetta, Traverso, Sonia, Elia, Laura, Picollo, Alessandra, Pusch, Michael, Camerino, Diana Conte
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573959/
https://ncbi.nlm.nih.gov/pubmed/12890704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705364
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