Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice

1. The purpose of this study was to synthesize novel valproyltaurine (VTA) derivatives including valproyltaurinamide (VTD), N-methyl-valproyltaurinamide (M-VTD), N,N-dimethyl-valproyltaurinamide (DM-VTD) and N-isopropyl-valproyltaurinamide (I-VTD) and evaluate their structure–pharmacokinetic–pharmac...

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Detalhes bibliográficos
Main Authors: Isoherranen, Nina, Yagen, Boris, Spiegelstein, Ofer, Finnell, Richard H, Merriweather, Michelle, Woodhead, Jose H, Wlodarczyk, Bogdan, White, H Steve, Bialer, Meir
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573897/
https://ncbi.nlm.nih.gov/pubmed/12812999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705301
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