Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents

1. Propylisopropyl acetamide (PID) is a new chiral amide derivative of valproic acid. The purpose of this study was to evaluate the anticonvulsant activity of PID in rodent models of partial, secondarily generalized and sound-induced generalized seizures which focus on different methods of seizure i...

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Main Authors: Isoherranen, Nina, Yagen, Boris, Woodhead, José H, Spiegelstein, Ofer, Blotnik, Simcha, Wilcox, Karen S, Finnell, Richard H, Bennett, Gregory D, White, H Steve, Bialer, Meir
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573693/
https://ncbi.nlm.nih.gov/pubmed/12598414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705076
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