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Different molecular sites of action for the K(ATP) channel inhibitors, PNU-99963 and PNU-37883A
1. We investigated the mechanism of action of two novel nonsulphonylurea ATP-sensitive potassium channel (K(ATP)) inhibitors, PNU-99963 and PNU-37883A, on four types of cloned K(ATP) channels. 2. Whole-cell currents were recorded in a symmetrical potassium (140 mM) gradient in HEK-293 cells stably e...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573826/ https://ncbi.nlm.nih.gov/pubmed/12746230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705228 |
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