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The molecular basis of the specificity of action of K(ATP) channel openers

K(ATP) channels incorporate a regulatory subunit of the ATP-binding cassette (ABC) transporter family, the sulfonylurea receptor (SUR), which defines their pharmacology. The therapeutically important K(+) channel openers (e.g. pinacidil, cromakalim, nicorandil) act specifically on the SUR2 muscle is...

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Autores principales: Moreau, Christophe, Jacquet, Hélène, Prost, Anne-Lise, D’hahan, Nathalie, Vivaudou, Michel
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC305901/
https://ncbi.nlm.nih.gov/pubmed/11118199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.24.6644
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