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K(ATP) channel expression and pharmacological in vivo and in vitro studies of the K(ATP) channel blocker PNU-37883A in rat middle meningeal arteries

BACKGROUND AND PURPOSE: Dilatation of cerebral and dural arteries causes a throbbing, migraine-like pain, indicating that these structures are involved in migraine. Clinical trials suggest that adenosine 5′-triphosphate-sensitive K(+) (K(ATP)) channel opening may cause migraine by dilatating intracr...

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Bibliografische gegevens
Hoofdauteurs: Ploug, K B, Boni, L J, Baun, M, Hay-Schmidt, A, Olesen, J, Jansen-Olesen, I
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438990/
https://ncbi.nlm.nih.gov/pubmed/18332850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.86
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