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Inhibitory mechanism of xestospongin-C on contraction and ion channels in the intestinal smooth muscle

1. Xestospongin-C isolated from a marine sponge, Xestospongia sp., has recently been shown to be a membrane-permeable IP(3) receptor inhibitor. In this study we examined the effects of this compound on smooth muscle from guinea-pig ileum. 2. In guinea-pig ileum permeabilized with α-toxin, xestospong...

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Detalhes bibliográficos
Main Authors: Ozaki, Hiroshi, Hori, Masatoshi, Kim, Yoon-Sun, Kwon, Seong-Chun, Ahn, Duck-Sun, Nakazawa, Hiroshi, Kobayashi, Motomasa, Karaki, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573613/
https://ncbi.nlm.nih.gov/pubmed/12466229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704988
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