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Xestospongin C, a selective and membrane-permeable inhibitor of IP(3) receptor, attenuates the positive inotropic effect of α-adrenergic stimulation in guinea-pig papillary muscle
1. We evaluated the role of the inositol 1,4,5-triphosphate (IP(3)) receptor-mediated Ca(2+) release on the positive inotropic effects of α-adrenergic stimulation using a novel, potent, selective membrane-permeable blocker of IP(3) receptor, xestospongin C. 2. Guinea-pig papillary muscle permeabiliz...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572115/ https://ncbi.nlm.nih.gov/pubmed/10821794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703358 |
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