Superoxide anions mediate veratridine-induced cytochrome c release and caspase activity in bovine chromaffin cells

1. Mitochondrial mechanisms involved in veratridine-induced chromaffin cell death have been explored. 2. Exposure to veratridine (30 μM, 1 h) produces cytochrome c release to the cytoplasm that seems to be mediated by superoxide anions and that is blocked by cyclosporin A (10 μM), MnTBAP (10 nM), ca...

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Dettagli Bibliografici
Autori principali: Jordán, Joaquín, Galindo, María F, Tornero, Daniel, Benavides, Amparo, González, Constancio, Agapito, María T, González-Garcia, Carmen, Ceña, Valentín
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573576/
https://ncbi.nlm.nih.gov/pubmed/12429571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704953
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