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Superoxide anions mediate veratridine-induced cytochrome c release and caspase activity in bovine chromaffin cells
1. Mitochondrial mechanisms involved in veratridine-induced chromaffin cell death have been explored. 2. Exposure to veratridine (30 μM, 1 h) produces cytochrome c release to the cytoplasm that seems to be mediated by superoxide anions and that is blocked by cyclosporin A (10 μM), MnTBAP (10 nM), ca...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573576/ https://ncbi.nlm.nih.gov/pubmed/12429571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704953 |
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