Direct and indirect inhibition by nociceptin/orphanin FQ on noradrenaline release from rodent cerebral cortex in vitro

1. The modulation exerted by nociceptin/orphanin FQ (NC) on noradrenaline (NE) release in rodent cerebral cortex slices and synaptosomes was studied. 2. Rat, mouse and guinea-pig cortical slices and synaptosomes were preincubated with 0.1 μM [(3)H]-NE and superfused. NE release was evoked by 2 min o...

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Autori principali: Siniscalchi, Anna, Rodi, Donata, Morari, Michele, Marti, Matteo, Cavallini, Sabrina, Marino, Silvia, Beani, Lorenzo, Bianchi, Clementina
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573458/
https://ncbi.nlm.nih.gov/pubmed/12163351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704841
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