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Sirolimus/cyclosporine/tacrolimus interactions on bile flow and biliary excretion of immunosuppressants in a subchronic bile fistula rat model

1. The new immunosuppressive agent sirolimus generally is combined in transplant patients with cyclosporine and tacrolimus which both exhibit cholestatic effects. Nothing is known about possible cholestatic effects of these combinations which might be important for biliary excretion of endogenous co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deters, Michael, Klabunde, Til, Kirchner, Gabriele, Resch, Klaus, Kaever, Volkhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573383/
https://ncbi.nlm.nih.gov/pubmed/12055139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704756
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