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Mechanisms of action of proteinase-activated receptor agonists on human platelets

1. We studied the activation of human platelets by thrombin and proteinase activated receptor (PAR)-activating peptides (PAR-APs) [SFLLRNPNDKYEPF-amide (TRAP), TFLLR-amide (PAR1AP) and AYPGKF-amide (PAR4AP)]. 2. PAR agonist-induced platelet aggregation, glycoprotein (GP) Ib and GPIIb/IIIa surface ex...

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Bibliografiske detaljer
Main Authors: Chung, Ada W Y, Jurasz, Paul, Hollenberg, Morley D, Radomski, Marek W
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573223/
https://ncbi.nlm.nih.gov/pubmed/11877318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704559
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