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Transient relaxation of rat mesenteric microvessels by ceramides

1. We have investigated the vasodilating effects of D-erythro-C2-ceramide (C2-ceramide) in methoxamine-contracted rat mesenteric microvessels. 2. C2-ceramide (10–100 μM) caused a concentration-dependent, slowly developing relaxation which reached maximum values after ≈10 min and partially abated the...

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Bibliographic Details
Main Authors: Czyborra, Peter, Saxe, Miriam, Fetscher, Charlotte, Meyer zu Heringdorf, Dagmar, Herzig, Stefan, Jakobs, Karl H, Michel, Martin C, Bischoff, Angela
Format: Artigo
Language:Inglês
Published: 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573158/
https://ncbi.nlm.nih.gov/pubmed/11815377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704498
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