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Comparison of the affinity of β-blockers for two states of the β(1)-adrenoceptor in ferret ventricular myocardium
1. We compared the potency of 11 clinically available β-blockers as antagonists of the positive inotropic effects of (−)-isoprenaline and CGP12177 on ferret ventricular myocardium. 2. (−)-CGP12177, (−)-pindolol and (−)-alprenolol were non-conventional partial agonists with intrinsic activity of 0.7,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573134/ https://ncbi.nlm.nih.gov/pubmed/11815381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704450 |
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