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Differential regulation of endobiotic-oxidizing cytochromes P450 in vitamin A-deficient male rat liver

1. The hepatic CYP4A-dependent ω-hydroxylation of arachidonic acid and CYP2C11-dependent 2α-/16α-hydroxylations of testosterone were decreased to 74 and 60% of respective control in microsomal fractions from vitamin A-deficient rats. Decreases in the rates of arachidonic acid ω-1-hydroxylation and t...

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Detalhes bibliográficos
Main Authors: Murray, Michael, Sefton, Rachel M, Croft, Kevin D, Butler, Alison M
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573074/
https://ncbi.nlm.nih.gov/pubmed/11724755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704380
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