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Effect of P-glycoprotein modulators on the pharmacokinetics of camptothecin using microdialysis

1. By performing microdialysis, this study investigated the pharmacokinetics of unbound camptothecin in rat blood, brain and bile in the presence of P-glycoprotein mediated transport modulators (cyclosporin A, berberine, quercetin, naringin and naringenin). Pharmacokinetic parameters of camptothecin...

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Bibliografske podrobnosti
Main Authors: Tsai, T H, Lee, C H, Yeh, P H
Format: Artigo
Jezik:Inglês
Izdano: 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573054/
https://ncbi.nlm.nih.gov/pubmed/11704644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704363
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