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Pharmacokinetics of pefloxacin and its interaction with cyclosporin A, a P-glycoprotein modulator, in rat blood, brain and bile, using simultaneous microdialysis
1. In vivo microdialysis with HPLC was used to investigate the pharmacokinetics of pefloxacin and its interaction with cyclosporin A. Microdialysis probes were inserted into the jugular vein/right atrium, the striatum and the bile duct of male Sprague-Dawley rats. Biological fluid sampling thereby a...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572663/ https://ncbi.nlm.nih.gov/pubmed/11250882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703927 |
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