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Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist

Endostatin is a potent endogenous inhibitor of angiogenesis that was recently shown to be stored in platelets and released in response to thrombin, but not ADP. In the present study, we have tested the hypothesis that thrombin-induced endostatin release from rat platelets is mediated via proteinase-...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ma, Li, Hollenberg, Morley D, Wallace, John L
פורמט: Artigo
שפה:Inglês
יצא לאור: 2001
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573005/
https://ncbi.nlm.nih.gov/pubmed/11606309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704312
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