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Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist
Endostatin is a potent endogenous inhibitor of angiogenesis that was recently shown to be stored in platelets and released in response to thrombin, but not ADP. In the present study, we have tested the hypothesis that thrombin-induced endostatin release from rat platelets is mediated via proteinase-...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573005/ https://ncbi.nlm.nih.gov/pubmed/11606309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704312 |
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