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Adenosine A(2A) receptor antagonists are potential antidepressants: evidence based on pharmacology and A(2A) receptor knockout mice

1. Adenosine, an ubiquitous neuromodulator, and its analogues have been shown to produce ‘depressant' effects in animal models believed to be relevant to depressive disorders, while adenosine receptor antagonists have been found to reverse adenosine-mediated ‘depressant' effect. 2. We have...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yacoubi, Malika El, Ledent, Catherine, Parmentier, Marc, Bertorelli, Rosalia, Ongini, Ennio, Costentin, Jean, Vaugeois, Jean-Marie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572930/
https://ncbi.nlm.nih.gov/pubmed/11522598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704240
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