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Adenosine A(2A) receptor antagonists are potential antidepressants: evidence based on pharmacology and A(2A) receptor knockout mice
1. Adenosine, an ubiquitous neuromodulator, and its analogues have been shown to produce ‘depressant' effects in animal models believed to be relevant to depressive disorders, while adenosine receptor antagonists have been found to reverse adenosine-mediated ‘depressant' effect. 2. We have...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572930/ https://ncbi.nlm.nih.gov/pubmed/11522598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704240 |
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