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A kinetic study on the stereospecific inhibition of KCNQ1 and I(Ks) by the chromanol 293B
1. Recently we and others have demonstrated a stereoselective inhibition of slowly activating human I(Ks) (KCNQ1/MinK) and homomeric KCNQ1 potassium channels by the enantiomers of the chromanol 293B. Here, we further characterized the mechanism of the 293B block and studied the influence of the 293B...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572901/ https://ncbi.nlm.nih.gov/pubmed/11739240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704421 |
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