Chromanol 293B, an inhibitor of KCNQ1 channels, enhances glucose-stimulated insulin secretion and increases glucagon-like peptide-1 level in mice

Glucose-stimulated insulin secretion (GSIS) is a highly regulated process involving complex interaction of multiple factors. Potassium voltage-gated channel subfamily KQT member 1 (KCNQ1) is a susceptibility gene for type 2 diabetes (T2D) and the risk alleles of the KCNQ1 gene appear to be associate...

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Vydáno v:Islets
Hlavní autoři: Liu, Lijie, Wang, Fanfan, Lu, Haiying, Ren, Xiaomei, Zou, Jihong
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588556/
https://ncbi.nlm.nih.gov/pubmed/25437377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19382014.2014.962386
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