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Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats

1. Fibrosis leads to chronic impairment of cardiac and renal function and thus reversal of existing fibrosis may improve function and survival. This project has determined whether pirfenidone, a new antifibrotic compound, and spironolactone, an aldosterone antagonist, reverse both deposition of the...

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Bibliografski detalji
Glavni autori: Miric, Goran, Dallemagne, Catherine, Endre, Zoltan, Margolin, Solomon, Taylor, Stephen M, Brown, Lindsay
Format: Artigo
Jezik:Inglês
Izdano: 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572838/
https://ncbi.nlm.nih.gov/pubmed/11429393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704131
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