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Respective contributions of α-adrenergic and non-adrenergic mechanisms in the hypotensive effect of imidazoline-like drugs
1. The hypotensive effect of imidazoline-like drugs, such as clonidine, was first attributed to the exclusive stimulation of central α(2)-adrenoceptors (α(2)ARs). 2. However, a body of evidence suggests that non-adrenergic mechanisms may also account for this hypotension. 3. This work aims (i) to ch...
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| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572786/ https://ncbi.nlm.nih.gov/pubmed/11350862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704080 |
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