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LNP 906, the first high-affinity photoaffinity ligand selective for I(1) imidazoline receptors

1. The hypotensive effect of imidazoline-like drugs, such as clonidine, was attributed both to α(2)-adrenergic receptors and nonadrenergic imidazoline receptors, which are divided into I(1), I(2) and I(3) subtypes. 2. We have recently synthesized a derivative of (2-(2-chloro-4-iodo-phenylamino)-5-me...

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Detalhes bibliográficos
Main Authors: Dragan, Urosevic, Stephan, Schann, Jean-Daniel, Ehrhardt, Pascal, Bousquet, Hugues, Greney
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574957/
https://ncbi.nlm.nih.gov/pubmed/15178642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705784
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