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Functional characterization of a human receptor for neuropeptide FF and related peptides

1. Neuropeptides FF (NPFF) and AF (NPAF) are involved in pain modulation and opioid tolerance. These peptides were known to act through uncharacterized G protein-coupled receptors (GPCR). We describe here, using an aequorin-based assay as screening tool, that an orphan GPCR, previously designated HL...

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Autors principals: Kotani, Masato, Mollereau, Catherine, Detheux, Michel, Le Poul, Emmanuel, Brézillon, Stéphane, Vakili, Jalal, Mazarguil, Honoré, Vassart, Gilbert, Zajac, Jean-Marie, Parmentier, Marc
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572755/
https://ncbi.nlm.nih.gov/pubmed/11325803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704038
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