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The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm

1. The vasoactive peptide endothelin (ET) has been implicated in the pathogenesis of cerebral vasospasm following subarachnoid haemorrhage. In these studies we investigated the involvement of protein kinase C (PKC) in sustained vasoconstriction induced by ET-1 in canine cerebral arteries. We also ex...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wickman, Grant, Nessim, Mourad A, Cook, David A, Vollrath, Bozena
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572750/
https://ncbi.nlm.nih.gov/pubmed/11325788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704025
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