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The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm

1. The vasoactive peptide endothelin (ET) has been implicated in the pathogenesis of cerebral vasospasm following subarachnoid haemorrhage. In these studies we investigated the involvement of protein kinase C (PKC) in sustained vasoconstriction induced by ET-1 in canine cerebral arteries. We also ex...

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Detalhes bibliográficos
Main Authors: Wickman, Grant, Nessim, Mourad A, Cook, David A, Vollrath, Bozena
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572750/
https://ncbi.nlm.nih.gov/pubmed/11325788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704025
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